Preparation of FRET reporters to support chemical probe development
نویسندگان
چکیده
منابع مشابه
Preparation of FRET reporters to support chemical probe development.
In high throughput screening (HTS) campaigns, the quality and cost of commercial reagents suitable for pilot studies often create obstacles upon scale-up to a full screen. We faced such challenges in our efforts to implement an HTS for inhibitors of the phosphopantetheinyl transferase Sfp using an assay that had been validated using commercially available reagents. Here we demonstrate a facile ...
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I am gratified by the positive response to my recent review article (1), especially when it comes from the scientific group that made very significant contributions to the field of fluorescence resonance energy transfer probes. The papers mentioned in the letter are important and were not cited in the review because they were published after the final version of the review had already been subm...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2010
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c0ob00322k